Biodistributions of ¹¹¹In-DOTA-biotin in blood, marrow, spleen, and normal organs after pretargeting with anti-mCD45 Ab-SA conjugate. Leukemic SJL/J mice were injected via the tail vein with 0.67 nmol of anti-mCD45Ab-SA conjugate, administered either alone or 8 hours later with 5.8 nmol of CA, followed by 1.2 nmol of ¹¹¹In-labeled DOTA-biotin 10 hours after delivery of the Ab-SA conjugate in all mice. Mice were killed 24 hours later, and blood, marrow, spleen, and normal organs were harvested, weighed, and analyzed for levels of radioactivity by gamma counting to determine percent ID/g. Error bars are SD.