American Society of Hematology

Figure 3

$Figure 3. Regulatory activity of antigen-specific T-cell responses by autoantigen-specific Tr clones derived from a patient with AIHA. Tr clone P8(1) inhibits proliferation by unfractionated autologous CD4+ T cells responding to APCs presenting the Rh protein autoantigen. The ratio of clones to autologous CD4+ T cells was 1:50 (10 000) and 1:12.5 (40 000), respectively. Proliferation was measured after 96 hours at 37°C, 5% CO2. All data shown are representative of 4 separate experiments with clone P8(1), and similar results were obtained with the other lines obtained from the patient. Data are presented as mean plus or minus standard error.$

Regulatory activity of antigen-specific T-cell responses by autoantigen-specific Tr clones derived from a patient with AIHA. Tr clone P8(1) inhibits proliferation by unfractionated autologous CD4⁺ T cells responding to APCs presenting the Rh protein autoantigen. The ratio of clones to autologous CD4⁺ T cells was 1:50 (10 000) and 1:12.5 (40 000), respectively. Proliferation was measured after 96 hours at 37°C, 5% CO₂. All data shown are representative of 4 separate experiments with clone P8(1), and similar results were obtained with the other lines obtained from the patient. Data are presented as mean plus or minus standard error.

This Feature Is Available To Subscribers Only