Expression analysis of the hnRNP-K–, hnRNP-E2–, and La/SSB-associated mRNA products in BCR/ABL⁺ cells.(A) Western blots show levels of the candidate hnRNP-E2–, hnRNP-K–, and La/SSB-associated mRNA products in 32Dcl3 (lane 1) and in untreated and imatinib-treated 32D-BCR/ABL (lanes 2,3) and K562 (lanes 3,5) cells. Levels of La/SSB, hnRNP-E2, hnRNP-K, BCR/ABL (antiphosphotyrosine), and GRB2 were detected as controls. (B) Western blots show expression of hnRNP-E2, FOXO1A, PKC1β, and STAT3, and of hnRNP-K, LATS1, SIPA1, PKCb1, and DOCK4 in hnRNP-E2 (top panel) shRNA- and (bottom panel) hnRNP-K shRNA–transduced 32D-BCR/ABL, respectively. Expression in parental and BCR/ABL-expressing 32Dcl3 cells served as controls.