The consensus EUROclass classification scheme. The figure depicts the new consensus classification scheme according to transitional B cells (A) CD21^low B cells (B). B indicates total B cells; smB, switched memory B cells; Tr, transitional, and 21, CD21^low B cells. Patients in group B− with less than 1% B cells were not examined in this study. The prevalence of the respective clinical phenomena is listed for each subgroup, and significant differences in the prevalence between subgroups are indicated. Because data on transitional cells and CD21^low B cells were not available in 43 and 74 patients, respectively, the missing patients were excluded from the subgroup analysis. *P < .001 compared with smB+. +P < .01 compared with smB+. ‡P = .002 compared with smB− Tr^norm as well as to smB+. §P = .009 compared with smB+ 21^norm. ‖P = .049 compared with smB+ 21^norm. ¶P = .03 compared with smB− 21^norm and P < .001 compared with smB+ 21^norm, #P = .016 compared with smB+ 21^norm.