Figure 2
Figure 2. Intravenous administration of KC, MIP-2, and G-CSF stimulates the mobilization of neutrophils from the bone marrow into the blood. Mice injected intravenously with either 100 μL of PBS, KC, MIP-2, or G-CSF (660 nM each). The number of neutrophils per milliliter of blood (A) and the number of bone marrow neutrophils (per femur) (B) were determined 2 hours following injection. Results are expressed as means plus or minus SEM (n = 4 mice). *P < .05; **P < .01 (1-way ANOVA and Dunnett test).

Intravenous administration of KC, MIP-2, and G-CSF stimulates the mobilization of neutrophils from the bone marrow into the blood. Mice injected intravenously with either 100 μL of PBS, KC, MIP-2, or G-CSF (660 nM each). The number of neutrophils per milliliter of blood (A) and the number of bone marrow neutrophils (per femur) (B) were determined 2 hours following injection. Results are expressed as means plus or minus SEM (n = 4 mice). *P < .05; **P < .01 (1-way ANOVA and Dunnett test).

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