Figure 1
Figure 1. KC/MIP-2 and G-CSF but not GM-CSF contribute to blood and tissue neutrophilia in TG-induced peritonitis. Neutralizing antibodies against KC (50 μg), MIP-2 (20 μg), KC and MIP-2, G-CSF (150 μg), GM-CSF (50 μg), or rat isotype-control mAb (mixture of control isotype IgGs) were administered intraperitoneally 20 minutes before intraperitoneal injection of 3% thioglycollate (TG). The number of neutrophils per milliliter of blood (A) and the number of neutrophils per milliliter of peritoneal lavage fluid (B) were determined 2 hours following TG injection. Results are expressed as means plus or minus SEM. Data from 6 independent experiments are combined (n = 4-15 mice). **P < .01 (1-way ANOVA and Dunnett test).

KC/MIP-2 and G-CSF but not GM-CSF contribute to blood and tissue neutrophilia in TG-induced peritonitis. Neutralizing antibodies against KC (50 μg), MIP-2 (20 μg), KC and MIP-2, G-CSF (150 μg), GM-CSF (50 μg), or rat isotype-control mAb (mixture of control isotype IgGs) were administered intraperitoneally 20 minutes before intraperitoneal injection of 3% thioglycollate (TG). The number of neutrophils per milliliter of blood (A) and the number of neutrophils per milliliter of peritoneal lavage fluid (B) were determined 2 hours following TG injection. Results are expressed as means plus or minus SEM. Data from 6 independent experiments are combined (n = 4-15 mice). **P < .01 (1-way ANOVA and Dunnett test).

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