Figure 3
Figure 3. Inhibition of Treg cell–specific trafficking toward CSF supernatants with the use of anti-CCL17 and anti-CCL22 mAbs. CI-Treg of CSF supernatants obtained from patients with LM (n = 6) and CM (n = 3). After preincubation for 30 minutes at 4°C with anti-CCL17 and anti-CCL22 mAbs (1 μg/mL), Treg cell migration was tested by transwell migration assays. Symbols indicate CI-Treg of individual patients. Medians are indicated.

Inhibition of Treg cell–specific trafficking toward CSF supernatants with the use of anti-CCL17 and anti-CCL22 mAbs. CI-Treg of CSF supernatants obtained from patients with LM (n = 6) and CM (n = 3). After preincubation for 30 minutes at 4°C with anti-CCL17 and anti-CCL22 mAbs (1 μg/mL), Treg cell migration was tested by transwell migration assays. Symbols indicate CI-Treg of individual patients. Medians are indicated.

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