Inhibition of breast cancer metastasis by coagulation blocking anti-TF Mab-5G9. Luciferase-tagged MDA-MB-231 cells were mixed with 1 mg of control IgG1 (TIB115), Mab-5G9, or Mab-10H10 and injected into the tail vein of SCID mice. Bioluminescence was measured (A) and quantified based on photon flux (photons per second per square centimeter). (B) 4 hours and 1, 2, and 7 days after tumor cell injection; n = 8, t test; **P < .05.