Figure 3
FTY720 induced down-modulation Mcl-1 but not Bcl-2 in CLL B cells. Primary CLL cells (1 × 106 cells/mL medium) were incubated with 5 μM FTY720 for 4 hours and 8 hours. Cell lysates from different time points were subjected to Western blot analysis using anti–Mcl-1, anti–Bcl-2, and GAPDH antibody.
