Figure 2
![Figure 2. CD8+ T-cell responses to PR1 and WT1 vaccination by intracellular IFN-γ assay. (A-C) Longitudinal data on IFN-γ production by CD8+ T cells in PBMC samples from patient 8, cultured for 6 hours with PR1 (A), with WT1 (B), or without peptide (negative control [C]) are presented. Results are expressed as percentages of total CD8+ T cells. (D,E) Frequencies of PR1- and WT1-specific CD8+ T cells by tetramer analysis and IFN-γ production were compared and found to be highly correlated; P < .001.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/111/1/10.1182_blood-2007-08-108241/3/zh80020811290002.jpeg?Expires=1724176463&Signature=PUltN~j0Q2AlwXBGAC4dGA8VJQ2eSnRTC0H90hUw7abaOXggXO9azHX-0hvS03GEx~VF6DH0eYIM0zDrHO6mamer7xUrvE-M0yqzUDuMdLXgKRcKFzxabToKzt7q0NP4fPBsgSzSMXZEpGBgnOFyU1J9y3heGGxa-lj8~kyg9vDiFWZJJEOOq-g19R8Fye7V0LxKVnnZjCpe7SfXjZD0TwamabmBpRUsUdQsLHP4560cA37lEbZAoizyuGhhWaP23WCZiNI0eaPDFESO1IzICIxd6fpi-T8KA~hSMXdSuz4~ytk~MLFmPDPGEyqYBQ1cp4kYvs3UDuiqEUp4fmewlw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
CD8+ T-cell responses to PR1 and WT1 vaccination by intracellular IFN-γ assay. (A-C) Longitudinal data on IFN-γ production by CD8+ T cells in PBMC samples from patient 8, cultured for 6 hours with PR1 (A), with WT1 (B), or without peptide (negative control [C]) are presented. Results are expressed as percentages of total CD8+ T cells. (D,E) Frequencies of PR1- and WT1-specific CD8+ T cells by tetramer analysis and IFN-γ production were compared and found to be highly correlated; P < .001.
