Survival of mice that received transplants. Survival curves of mice that received transplants of BM cells expressing Cdx2 (n = 25), the W167A-CDX2 mutant (n = 14), or the ΔN-Cdx2 mutant (n = 13). The control group received transplants of BM infected with the EGFP control retrovirus (n = 10). The survival time of secondary recipient mice that received transplants of BM from diseased primary animals from the Cdx2 or W167A-CDX2 cohort is indicated. Tx indicates transplantation.