Figure 2
![Figure 2. AICD in lymphocytes from Fas-defective patients and healthy controls. TSST-1 AICD (B) was compared with Fas sensitivity (A) of T cells from 6 ALPS-I patients (P1 to P6), from 2 healthy mutation positive relatives (fP1 and fP6), and from eight age-related control donors. Experiments were performed as described in Figure 1 using TSST-1/TSST-1 activation/restimulation. The shaded gray zones indicate means of apoptosis induced by Fas or TSST-1 AICD in control-cells (n = 21; in panel A, mean = 89% ± 2% [SEM]; in panel B, mean = 68% ± 2%).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/110/13/10.1182_blood-2007-05-088286/3/zh80240710300002.jpeg?Expires=1724259047&Signature=dO-z9ji2WhzSLe1Q~NwsGDvtpMdm8XzIt5O-nV8LUBzLSqwH3Q2dGve~aJTqL2stCVsHqbdjjyr-cxCREQDX2jvcDzRkF5kwU7no6hFX5zejGwVGxqfp6H-vZWf0IVLfkHoBcRkS2GZlHXmP72MI4ny7pwkpJPX-dpvVN580ttnC412PBoZVMYOJ3glKDTomSNObYlMxF2uxnCCDpDIwXGUpGSszl-9IuVkg4A2eDE-M89KJ6nzN-DlLOiiZSzOCg-eZ-rplHKlipAQQGA3EVzT4hKZGCILkUQZadqmGdL3ORYbAMj3VJQtp4Yg3G5-91u53mhwaLXybK4DhXbMLGw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
AICD in lymphocytes from Fas-defective patients and healthy controls. TSST-1 AICD (B) was compared with Fas sensitivity (A) of T cells from 6 ALPS-I patients (P1 to P6), from 2 healthy mutation positive relatives (fP1 and fP6), and from eight age-related control donors. Experiments were performed as described in Figure 1 using TSST-1/TSST-1 activation/restimulation. The shaded gray zones indicate means of apoptosis induced by Fas or TSST-1 AICD in control-cells (n = 21; in panel A, mean = 89% ± 2% [SEM]; in panel B, mean = 68% ± 2%).
