Inducible expression of MHCII and increased MHCI with IFN-γ. Unactivated UTCs (gray, hollow curves) of both human (top panels) and porcine (bottom panels) origin express MHCI (left), but no MHCII (right). After 48 hours of incubation with IFN-γ, human and porcine activated UTCs (black, hollow curves) have increased expression of MHCI (left) and induced expression of MHCII (right). In all cases, staining was compared with an unstained negative control (black, filled).