Cation channel activity in on-cell patch recordings of DHSt red cells from patient SF. (A) Representative graphs of channel activity in on-cell patches from an unrelated normal cell (above) and a DHSt red cell from patient SF. (B) NPo of channel activity in DHSt red cells from patient SF (n = 4), from an unrelated volunteer (Control, n = 3) and from patient SF in the presence of pipet GsMTx-4 (2.5 μM; n = 3); *P < .05. (C) I-V curve of a representative on-cell patch record from a DHSt red cell of patient SF.