Identification of genes differentially expressed in WT CD19⁺B220^hiCD5⁻ B cells and CD19⁺CD5⁺ B cells from dnRAG1, Eμ-TCL1, and DTG mice at 12 weeks. (A) Unsupervised hierarchical clustering of a set of 107 genes that meet the filtering criterion which set the SD for logged data between 0.85 and 1000, and the expression level at >5 in 25% of the samples. (B) A list of common genes among the 50 genes that display the greatest differential expression in WT CD19⁺B220^hiCD5⁻ B cells relative to CD19⁺CD5⁺ B cells from all transgenic mice is shown in the top panel. For this analysis, pairwise comparisons were performed using the lower 90% confidence bound interval for genes with ±1.2-fold change filtering criterion. Genes with a mean expression value of <50 in a comparison pair were not included. A list of common genes among the 50 genes that display the greatest differential expression in CD19⁺CD5⁺ B cells from dnRAG1 and DTG mice relative to Eμ-TCL1 mice is also shown in the bottom panel.