Glutathione ratios (GSH:GSSG) of ITP patients and normal controls. GSH and GSSG concentrations were measured in patients with acute ITP (Acute ITP, n=34), chronic ITP (Chronic ITP, n=33), and pediatric controls (n=24). GSH:GSSG ratios were calculated for each sample (mean + SEM). GSH:GSSG ratios are significantly lower in all ITP patients (All ITP= Acute ITP + Chronic ITP, p<0.0001) compared to controls. Furthermore, GSH:GSSG ratios are significantly lower in patients with chronic ITP compared to controls (p=0.0002), in patients with acute ITP compared to controls (p=0.0018), and in patients with chronic ITP compared to patients with acute ITP (p=0.0192).