Expression of stem cell-related signatures predicts overall survival. The median expression of a) the 25 probe LSC signature or b) the 225 probe HSC signature was determined in 160 cytogenetically normal AML samples and used to stratify the patients into two groups of 80. All the patients had been treated with intensive double-induction therapy and consolidation chemotherapy. Expression was scaled to 0 for each probe. A Kaplan-Meier plot was generated and statistical significance determined by log-rank test.