Univariate associations to OS per data set per marker. Hazard ratios and 95% confidence intervals are denoted by diamond shape and whiskers, respectively. Markers which cross the center line are not significant. Panels separated by dashed lines contain statistic values per marker for all data sets. The order of the data sets is given on the top left, i.e. from top to bottom APEX, UAMS-TT3, UAMS-TT2, MRC-IX and HOVON65/GMMG-HD4 per panel. Generally, FISH markers (top) are less robust than GEP markers (bottom).