Figure 1.
Figure 1. Key significant gene analysis ofFASN inhibition inDLBCL cells. Cerulenin treatment in ABC OCI-LY3 shows (A) downregulation of growth promoting cytokines and growth factors and favorable tumor biology with predicted inhibition of tumor progression. In the GC derived SUDHL10 cells, (B) cerulenin resulted in activation of genes associated with oxidative stress response and PI3K associated mitochondrial genes with adverse tumor biology predicting tumor progression in GC DLBCL.

Key significant gene analysis ofFASN inhibition inDLBCL cells. Cerulenin treatment in ABC OCI-LY3 shows (A) downregulation of growth promoting cytokines and growth factors and favorable tumor biology with predicted inhibition of tumor progression. In the GC derived SUDHL10 cells, (B) cerulenin resulted in activation of genes associated with oxidative stress response and PI3K associated mitochondrial genes with adverse tumor biology predicting tumor progression in GC DLBCL.

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