Green box indicates low risk SCD with a PPV of two-year mortality of <10%. Yellow box is moderate risk SCD with a PPV of two-year mortality of 10% to 15%. Red box is high risk SCD with a PPV of two-year mortality of > 15%.

Figure 1B:Red: Patients at highest risk for 2-year (15%) mortality (red boxes, Figure 1A) may be considered for all risk category HSCTs including alternate donors with which there is no published data in adults (e.g. cord blood).