LSCs are more sensitive to ATG mediated CDC than healthy HSCs. Mononuclear cells from 15 patients newly diagnosed with AML and cells from leukapheresis products of 15 healthy stem cell donors were incubated with ATG (50 mg/L) in the presence of complement. After 15 minutes, the percentage of dead (7AAD⁺) cells was measured in LSCs and HSCs. Adjusted percentage (background subtracted) is shown for each patient/donor. Medians are shown as horizontal lines.