Figure 1. Loss of Plek2 Rescues The... | American Society of Hematology

Figure 1.

Loss of Plek2 Rescues The Lethality of JAK2^V617F Knockin Mice. (A) Kaplan-Meier survival analysis of indicated mice. Both males and females were included in each group. JAK2⁺^/+Plek2^+/+mice, n=34; JAK2⁺^/+Plek2^-/-mice, n=34;JAK2^VF/+Plek2^+/+ mice, n=36; JAK2^VF/+Plek2^-^/^- mice, n=36. (B) Kaplan-Meier survival analysis of the transplanted mice. JAK2⁺^/+Plek2^+/+mice, n=10; JAK2⁺^/+Plek2^-/-mice, n=10;JAK2^VF/+Plek2^+/+ mice, n=17; JAK2^VF/+Plek2^-^/^- mice, n=17.

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