Echocardiographic parameters evaluating diastolic function of the heart of SS vs SS;p22phox^-/-mice. A. Left atrial dimension (LAd). B. Isovolumic relaxation time (IVRT). SS: Hbb^{tm2(HBG1,HBB*)Tow} (UAB) with wild-type p22phox; SS;p22phox^-/-: UAB mice with targetted deletion of p22phox.(statistical analysis was performed using Wilcoxon rank-sum test; JMP 9.0 SAS Institute, Cary, North Carolina)