Figure 2.
Figure 2. The Fanconi anemia pathway. / FA proteins (A, B, C, D1, D2, E, F, G, I, J, L, M) are depicted with shaded circles. Additional DNA repair proteins interacting with the FA pathway are denoted in open circles. Following activation of the FA complex by DNA damage or the cell cycle, the D2 protein is monoubiquitinated. Monoubiquitinated D2 protein translocates to chromatin where it co-localizes with additional DNA repair proteins.

The Fanconi anemia pathway.

FA proteins (A, B, C, D1, D2, E, F, G, I, J, L, M) are depicted with shaded circles. Additional DNA repair proteins interacting with the FA pathway are denoted in open circles. Following activation of the FA complex by DNA damage or the cell cycle, the D2 protein is monoubiquitinated. Monoubiquitinated D2 protein translocates to chromatin where it co-localizes with additional DNA repair proteins.

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