Platelet count nadirs in heparin-induced thrombocytopenia (HIT), quinine-induced immune thrombocytopenic purpura (Q-ITP), and thrombotic thrombocytopenic purpura (TTP) with absent ADAMTS-13 activity.

The data for HIT, including the breakdown between patients with and without HIT-associated thrombosis, are published elsewhere (and reprinted with permission).¹³ The curve for Q-ITP is estimated from published data,¹⁴ and the data for TTP were kindly provided by Dr. James George (with permission).