Characteristics of mHAs by HLA type and donor relation. (A) There is a large difference in the number of peptides that can bind with high affinity to class I HLAs (0.09 to 1.32 per gMM). (B) MUD SCT is associated with roughly twice as many class I mHAs compared with MRD SCT. (C) Because of variable frequencies of peptide presentation by different HLA molecules, there is a greater variability in the mHAs compared with gMMs among both MRD and MUD patients. (D) There is a linear association between the number of GVL mHAs and GVHD mHAs. (E) There is no association between the number of GVL mHAs and relapse for MRD or MUD. (F) There is similarly no association between the number of GVH mHAs and GVHD.