Coagulation assay end points correlate with CSF NF-L levels. (A) Trend toward a positive correlation between R2 and NF-L. (B) Trend toward a negative correlation between alpha (rate of clot formation) and NF-L. (C) Significant positive correlation between clot start time and NF-L. (D) Significant negative correlation between Vmax and NF-L. Correlations were assessed for all subjects via Pearson’s method. r = Pearson’s correlation coefficient.