Figure 6.
Effect of ODSH on intramedullary PF4 levels. (A) hPF4+/Cxcl4−/− marrow 48 hours after irradiation stained with anti-hPF4 antibody. (B) Same as panel A, but for hPF4+/Cxcl4−/− marrow treated with a total of 75 mg/kg ODSH. (C) As in panel A, but for WT animal without irradiation. (D) As in panel B, but for WT animal treated with ODSH without irradiation. (E) Same as panel C, but 48 hours after irradiation in a WT animal (treated with PBS). (F) Same as panel D, but 48 hours after irradiation in a WT animal treated with ODSH. For all panels, scale bar = 100 µm; immunohistochemical stain and counterstained with hematoxylin.

Effect of ODSH on intramedullary PF4 levels. (A) hPF4+/Cxcl4−/− marrow 48 hours after irradiation stained with anti-hPF4 antibody. (B) Same as panel A, but for hPF4+/Cxcl4−/− marrow treated with a total of 75 mg/kg ODSH. (C) As in panel A, but for WT animal without irradiation. (D) As in panel B, but for WT animal treated with ODSH without irradiation. (E) Same as panel C, but 48 hours after irradiation in a WT animal (treated with PBS). (F) Same as panel D, but 48 hours after irradiation in a WT animal treated with ODSH. For all panels, scale bar = 100 µm; immunohistochemical stain and counterstained with hematoxylin.

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