Figure 5.
Figure 5. ODSH in RIT in WT animals. (A) Platelet counts of WT C57BL/6 animals as percentage of baseline platelet count after irradiation, showing statistically different platelet counts starting at day 8 postirradiation in animals treated with ODSH (25 mg/kg) starting 24 hours after irradiation and continuing for 3 doses every 12 hours. N = 15 animals per arm. P values by the Student t test after Bonferroni correction. (B) Same as panel A, but showing survival of irradiated animals. N = 15 animals per arm. P < .004 for survival difference by the Gehan-Breslow-Wilcoxon test.

ODSH in RIT in WT animals. (A) Platelet counts of WT C57BL/6 animals as percentage of baseline platelet count after irradiation, showing statistically different platelet counts starting at day 8 postirradiation in animals treated with ODSH (25 mg/kg) starting 24 hours after irradiation and continuing for 3 doses every 12 hours. N = 15 animals per arm. P values by the Student t test after Bonferroni correction. (B) Same as panel A, but showing survival of irradiated animals. N = 15 animals per arm. P < .004 for survival difference by the Gehan-Breslow-Wilcoxon test.

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