American Society of Hematology

Figure 1.

Inhibition or genetic deletion of FXIII(a) results in decreased clot weight. Whole blood from F13a+/+, F13a+/−, and F13a−/− mice was clotted with TF/CaCl2 in the absence or presence of the FXIII inhibitor T101 (20 µM, final) for 2 hours. (A-B) Serum RBC content (A) and contracted whole blood clot weight (B) were recorded. Each dot is a separate mouse; lines indicate mean ± SEM.

Inhibition or genetic deletion of FXIII(a) results in decreased clot weight. Whole blood from F13a^+/+, F13a^+/−, and F13a^−/− mice was clotted with TF/CaCl₂ in the absence or presence of the FXIII inhibitor T101 (20 µM, final) for 2 hours. (A-B) Serum RBC content (A) and contracted whole blood clot weight (B) were recorded. Each dot is a separate mouse; lines indicate mean ± SEM.

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