Figure 2.
Figure 2. Outcome of CMV enterocolitis in patient 5 post–CMV-specific VST infusion. (A) Viral load, lymphocyte count, and colonic biopsy in patient 5, who was treated with a single VST infusion. The patient had persistent symptomatic biopsy–proven CMV enterocolitis after a month of antiviral therapy. Post–VST infusion, the symptoms resolved, the patient developed an absolute lymphocytosis, and viral load fluctuated between negative and below the level of quantitation (<150 cp/mL). (B) CMV pp65-specific T-cell response as measured by IFN-γ ELIspot. (C-D) Photomicrograph of colonic biopsy with CMV immunostain pre–VST (C) and post–VST (D) infusion (original magnification ×200, Olympus microscope, model BX43). LLQ, lower limit of quantitation.

Outcome of CMV enterocolitis in patient 5 post–CMV-specific VST infusion. (A) Viral load, lymphocyte count, and colonic biopsy in patient 5, who was treated with a single VST infusion. The patient had persistent symptomatic biopsy–proven CMV enterocolitis after a month of antiviral therapy. Post–VST infusion, the symptoms resolved, the patient developed an absolute lymphocytosis, and viral load fluctuated between negative and below the level of quantitation (<150 cp/mL). (B) CMV pp65-specific T-cell response as measured by IFN-γ ELIspot. (C-D) Photomicrograph of colonic biopsy with CMV immunostain pre–VST (C) and post–VST (D) infusion (original magnification ×200, Olympus microscope, model BX43). LLQ, lower limit of quantitation.

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