Figure 3.
Figure 3. Tolerance induction of allogeneic TCD donor BM following transplantation of megadose BM and PTCY. (A) Limiting dilution analysis of CTL-p performed against donor (yellow) or third-party (green) splenocytes. A typical experiment assessing 1 chimeric mouse out of 3 tested is shown. (B) Acceptance of donor-type (BALB/c, white fur, red arrows) skin implanted at 7 months after BM transplantation, with rejection of third-party grafts (C57BL/6, black fur, yellow arrows).

Tolerance induction of allogeneic TCD donor BM following transplantation of megadose BM and PTCY. (A) Limiting dilution analysis of CTL-p performed against donor (yellow) or third-party (green) splenocytes. A typical experiment assessing 1 chimeric mouse out of 3 tested is shown. (B) Acceptance of donor-type (BALB/c, white fur, red arrows) skin implanted at 7 months after BM transplantation, with rejection of third-party grafts (C57BL/6, black fur, yellow arrows).

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