Figure 1.
Marked enhancement of chimerism induction upon combining megadose TCD BM transplantation with PTCY. (A) Typical mixed chimerism detected by FACS analysis at day 180. (B-C) Cumulative results of 9 experiments including a total of 66 recipient mice treated by megadose TCD BM plus PTCY, measured at 210 to 300 days posttransplant. Data are presented by violin plot representing the distribution of percent donor chimerism (B) and percent donor chimera (C). Statistical analysis was performed by χ2 analysis. (D) Chimeric mice exhibit multilineage chimerism (green bars, donor; purple bars, host).
