Figure 6.
Surface phenotype of CDP and MDP compared with MODP and MOP. (A) Overview of cell surface marker expression on MODP, MOP, CDP, and MDP, according to our own flow cytometric analysis and literature data.6 Indicated in red are the markers used for definition and flow cytometric purification. (B) MODP, MOP, CDP, and MDP populations as a percentage of total live BM cells (mean ± SD; n = 3). (C) Contour plots showing CX3CR1, Flt3, c-Kit, CD16/32, or Ly6C and CD27 expression on MODP versus CDP (top), MOP versus MDP (middle), or all 4 progenitor populations (bottom) in 1 plot. Data are representative of 3 experiments.

Surface phenotype of CDP and MDP compared with MODP and MOP. (A) Overview of cell surface marker expression on MODP, MOP, CDP, and MDP, according to our own flow cytometric analysis and literature data. Indicated in red are the markers used for definition and flow cytometric purification. (B) MODP, MOP, CDP, and MDP populations as a percentage of total live BM cells (mean ± SD; n = 3). (C) Contour plots showing CX3CR1, Flt3, c-Kit, CD16/32, or Ly6C and CD27 expression on MODP versus CDP (top), MOP versus MDP (middle), or all 4 progenitor populations (bottom) in 1 plot. Data are representative of 3 experiments.

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