FLT3 PIA. PIA was measured on day +6 of induction, cycle 1 day +15 of consolidation therapy, and cycle 1 day +15 of maintenance sorafenib. Results are expressed as percent change in FLT3 autophosphorylation from baseline. Bars plot median and interquartile range for subjects with FLT3-ITD or FLT3-TKD.