Correlations of WNT gene expression with white blood cell composition in patients with septic shock follow age-related patterns. Whole-blood gene expression of (A) all patients with septic shock, or separated by age (B) 35-50 years or (C) >50 years, was correlated with white blood cell counts. Proximity of the correlation coefficients to 1 (direct correlation) and −1 (inverse correlation) is highlighted according to the depicted heat map scale. Correlation coefficients for correlations that meet statistical significance (P < .05) are highlighted. BASO, basophils; EOS, eosinophils; LYMPH, lymphocytes; MONO, monocytes; NEUT, neutrophils; WCC, white cell count.