Figure 4.
![Figure 4. Effect of anfibatide in mitigating spontaneous thrombocytopenia in Adamts13−/−mice. (A-B) Platelet counts before (day 0 [D0]), during (day 3 [D3]), and after (day 7 [D7]) anfibatide therapy in mice with initial platelet counts <400 000/μL and ≥400 000/μL, respectively. (C) The percentage of mice with any increase, 30%, and 50% increase in platelet counts after anfibatide therapy. (D) The nonlinear correlation between platelet count increment on day 3 (D3) and day 7 (D7) after anfibatide therapy compared with the initial (day 0 [D0]) platelet counts. * and ** indicate that P values are <.05 and <.01, respectively. ns, No statistical significance (P >.05).](https://ash.silverchair-cdn.com/ash/content_public/journal/bloodadvances/1/1/10.1182_bloodadvances.2016000711/3/advances000711f4.jpeg?Expires=1722437864&Signature=ZpQnRhZEiTMEEAa2bD-7UUQ1L8h0cD7Trlluq~jGFqYUUNzfGVhLz4zR-Bju79~0kLGXIztHGW1jsap58SmyffDIyCiLBA7fgPqLrmG8W9oVgittJqX7mF6p3NlfOHL8vXpAXTozLwyLT0oNzIMBtDeas8NHkx~26bDuDbi7DMhtfqB5uko3p9m-iQseDHfe9rPjTkkcQs~bfbr0erMdwTk8HJQW8pcEM1D~L0D8KlWUjd6Eaf1sK1B6mxRNZaLcc31ZUbnjH02qr2KI0~2CWcpZy6cuDQ8RETWQ93jQvAomnK6P1k~cORF1LUcO4p-wPeJk8Ai825vWTCPSsc0Ssg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Effect of anfibatide in mitigating spontaneous thrombocytopenia in Adamts13−/−mice. (A-B) Platelet counts before (day 0 [D0]), during (day 3 [D3]), and after (day 7 [D7]) anfibatide therapy in mice with initial platelet counts <400 000/μL and ≥400 000/μL, respectively. (C) The percentage of mice with any increase, 30%, and 50% increase in platelet counts after anfibatide therapy. (D) The nonlinear correlation between platelet count increment on day 3 (D3) and day 7 (D7) after anfibatide therapy compared with the initial (day 0 [D0]) platelet counts. * and ** indicate that P values are <.05 and <.01, respectively. ns, No statistical significance (P >.05).
