Kaplan Meier survival curves for 167 Stage A CLL patients. Summated FLC >50mg/L were combined with ß-2M >3.5mg/L to produce a three tiered risk stratification model. Patients with 0 (ß-2M <3.5mg/L + FLC <50mg/L, green, 75% untreated =212 months), 1 (ß-2M >3.5mg/L or FLC >50mg/L blue, 75% untreated = 131 months),or 2 (ß-2M >3.5mg/L and FLC >50mg/L red, 75% untreated = 46 months) risk factors had significantly overall survival times (p=5*10^-5)