American Society of Hematology

Figure 2.

$Figure 2. Relationship between number of platelet (plt) transfusions and plt increments at 1 hour and 18 to 24 hours after transfusion and days-to-next transfusion. / A) The mean 1-hour post-transfusion plt increments are plotted for the first 25 transfusions given to all study patients. These data represent 6334 transfusions given to 533 patients (•). Similar data for the 18- to 24-hour post-transfusion plt increments are shown for 5555 transfusions given to 531 patients (○). Data for days-to-next transfusion for 5955 transfusions given to 530 patients (▴). / B) When the same analyses are plotted for only lymphocytotoxic antibody-negative patients, the results are similar. One-hour increments for 5484 transfusions given to 477 patients (•), 18- to 24-hour increments for 4833 transfusions given to 475 patients (○), and days to next transfusion for 5144 transfusions given to 474 patients (▴). Dotted lines are best fit of the data for 1-hour post-transfusion increments; dashed lines, for 24-hour post-transfusion increments; and solid lines for days to next transfusion. / This research was originally published in Slichter SJ, Davis K, Enright H, et al. Factors affecting post-transfusion platelet increments, platelet refractoriness, and platelet transfusion intervals in thrombocytopenic patients. Blood. 2005;105:4106–4114. © The American Society of Hematology.$

Relationship between number of platelet (plt) transfusions and plt increments at 1 hour and 18 to 24 hours after transfusion and days-to-next transfusion.

A) The mean 1-hour post-transfusion plt increments are plotted for the first 25 transfusions given to all study patients. These data represent 6334 transfusions given to 533 patients (•). Similar data for the 18- to 24-hour post-transfusion plt increments are shown for 5555 transfusions given to 531 patients (○). Data for days-to-next transfusion for 5955 transfusions given to 530 patients (▴).

B) When the same analyses are plotted for only lymphocytotoxic antibody-negative patients, the results are similar. One-hour increments for 5484 transfusions given to 477 patients (•), 18- to 24-hour increments for 4833 transfusions given to 475 patients (○), and days to next transfusion for 5144 transfusions given to 474 patients (▴). Dotted lines are best fit of the data for 1-hour post-transfusion increments; dashed lines, for 24-hour post-transfusion increments; and solid lines for days to next transfusion.

This research was originally published in

Slichter SJ, Davis K, Enright H, et al. Factors affecting post-transfusion platelet increments, platelet refractoriness, and platelet transfusion intervals in thrombocytopenic patients. Blood. 2005;105:4106–4114.

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