CD14 overexpression on granulocytes of patients with del(5q) MDS. (A) Flow cytometric analysis of CD14 and CD11b levels in bone marrow granulocytes from patients with 5q− syndrome and healthy controls. (B) Quantitative analysis of CD14 levels of bone marrow granulocytes from indicated patient groups. 5q− syndrome: N = 11, mean ± SEM = 18.84 ± 7.97; other MDS (without del[5q]): N = 12, mean ± SEM = 2.25 ± 0.66; control: N = 21, mean ± SEM = 3.10 ± 0.30. (C) Immunohistochemistry stains of mDia1 of bone marrow sections from representative patients of indicated groups in panel B. Granulocytes are indicated by arrows. Megakaryocytes and lymphocytes with high mDia1 expression levels served as internal controls. Scale bars represent 30 μm.