Figure 4
Figure 4. Genome-wide occupation of BACH2 and MAFK in B cells. (A) Union analysis of BACH2 and MAFK peaks. Numbers indicate unique and overlapping peaks. ChIP-seq tracks for BACH2 and MAFK ChIP-seq are shown for the BACH2 gene. (B) The heat map represents the relative enrichment of transcription factor motifs overpresented in BACH2, MAFK, and BACH2/MAFK heterodimer peaks relative to random genomic regions. (C) A heat map is shown representing the relative enrichment of gene signatures among BACH2-MAFK target genes. The statistical significance is shown in the color key. P values were calculated by Fisher’s exact test with Benjamini-Hochberg correction.

Genome-wide occupation of BACH2 and MAFK in B cells. (A) Union analysis of BACH2 and MAFK peaks. Numbers indicate unique and overlapping peaks. ChIP-seq tracks for BACH2 and MAFK ChIP-seq are shown for the BACH2 gene. (B) The heat map represents the relative enrichment of transcription factor motifs overpresented in BACH2, MAFK, and BACH2/MAFK heterodimer peaks relative to random genomic regions. (C) A heat map is shown representing the relative enrichment of gene signatures among BACH2-MAFK target genes. The statistical significance is shown in the color key. P values were calculated by Fisher’s exact test with Benjamini-Hochberg correction.

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