Frequency of BCL2 and MYC expression in COO subtypes of DLBCL. (A) Relative frequency of the ABC vs GCB subtype in DLBCL positive for BCL2 expression, MYC expression, or MYC/BCL2 coexpression in the training set. (B) Frequency of BCL2 expression, MYC expression, or MYC/BCL2 coexpression (in the presence or absence of MYC/BCL2 corearrangements, DH) in DLBCL of the ABC and GCB subtypes in the training set. DH, double hit.