Figure 7
Figure 7. BAFF increases CXCL13- and CCL21-induced phosphorylation of PI3K/AKT, p38MAPK, and IκBα. Mock- and BAFF-treated B cells were stimulated for 2 minutes with medium, 100 ng/mL CXCL13, or 100 ng/mL CCL21. Phosphorylation of AKT, p38MAPK, PLCβ3, and IκBα was corrected for total relevant protein. The p52 contents in total-cell lysates were corrected for actin contents. Blots from one representative experiment are shown. Values reported for p52 contents and phosphorylation of AKT, p38MAPK, and IκBα are mean values plus or minus SD from 3 or 2 (PLCβ3) independent experiments.

BAFF increases CXCL13- and CCL21-induced phosphorylation of PI3K/AKT, p38MAPK, and IκBα. Mock- and BAFF-treated B cells were stimulated for 2 minutes with medium, 100 ng/mL CXCL13, or 100 ng/mL CCL21. Phosphorylation of AKT, p38MAPK, PLCβ3, and IκBα was corrected for total relevant protein. The p52 contents in total-cell lysates were corrected for actin contents. Blots from one representative experiment are shown. Values reported for p52 contents and phosphorylation of AKT, p38MAPK, and IκBα are mean values plus or minus SD from 3 or 2 (PLCβ3) independent experiments.

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