Prognostic influence of FLT3-TKD in APL. Overall survival (A) and event-free survival (B) of FLT3-TKD wild-type (FLT3-wt) vs FLT3-TKD mutated cases (FLT3-TKDmut) in t(15/17)/PML-RARA positive AML. Overall survival (C) and event-free survival (D) of FLT3-TKD wild-type (FLT3-wt) versus FLT3-TKD mutated cases (FLT3-TKDmut) in t(15/17)/PML-RARA positive AML exclusive all cases that are FLT3-LM mutated.