Increased anti-CD3–induced proliferation of gp130^F757/F757 T cells. (A) Purified, CFSE-labeled wt (+/+) or gp130^F757/F757 (gp130^F/F) LN T cells were stimulated for 3 days with anti-CD3 (10 μg/mL) and analyzed by flow cytometry. The profile of unstimulated, CFSE-labeled cells cultured for 3 days is indicated by the dotted lines. (B) Naive CD44^lo CD8⁺ LN T cells were purified by fluorescence-activated cell sorting and cultured as described for panel A. The division index shows the average number of cell divisions in each culture. Data are representative of 3 to 4 independent experiments.