Figure 7
Effect of HS1 deficiency on agonist-induced Akt phosphorylation. Washed platelets from wild-type and HS1-deficient mice were stimulated with either convulxin (A) or AYPGKF (B) for 1 minute, and Western blot analysis of serine-phosphorylated Akt (Ser473) was performed on total cell lysates. PKCĪ“ was used as a lane-loading control. The data are representative of at least 3 different experiments.
