Interaction of ABT007 Fab-EPOR. Crystal structure of the binding region of a single Fab-EPOR monomeric complex. Gray represents the ABT007 Fab light chain, brown represents the ABT007 Fab heavy chain, and green represents EPOR. Highlighted residues are directly involved in Fab/EPOR binding. Residues F93 and F205 of EPOR, highlighted in purple, are key residues involved in binding EPO and are not involved in Fab binding.