Consensus parsimony gene trees inferred from CPB2 haplotypes in European whites and Africans. (A) Gene tree constructed from 6 variant sites in the 5′ region (-2599C>G, -2345--2344insG, -1925T>C, -1690A>G, -1102G>T, and -438G>A). (B) Gene tree constructed from 7 variant sites in the coding/3′UTR region (310C>T, A147T [G>A], G633A, 678T>C, T325I [C>T], 1542C>G, and 1583T>A). The relative frequency of each haplotype is indicated by the area of the circle. Haplotypes with a frequency less than 0.02 are not taken into consideration. Full black circles correspond to haplotype not present in the samples. Loops indicate phylogenetic ambiguity due to recombination or to parallel, convergent, or reverse changes. Alleles in underlined bold correspond to the putative QTNs (-2599C>G, -2345--2344insG, and 1583T>A).