Figure 7.
Figure 7. Cells expressing CM show altered expression of known inv(16)-associated transcripts. (A) qPCR analysis of samples from CD34 magnetically purified cells from CM and control nontransduced CB cultures. Error bars represent SD of 2 to 6 samples. (B) Gel electrophoresis of SDR1 and c-abl amplicons after 40 rounds of qPCR amplification. Samples are derived from CD34+ cells from 2 CM cultures (CM17 and CM6) and 3 different long-term control CB cultures (CB952A, CB935A, and CB56).

Cells expressing CM show altered expression of known inv(16)-associated transcripts. (A) qPCR analysis of samples from CD34 magnetically purified cells from CM and control nontransduced CB cultures. Error bars represent SD of 2 to 6 samples. (B) Gel electrophoresis of SDR1 and c-abl amplicons after 40 rounds of qPCR amplification. Samples are derived from CD34+ cells from 2 CM cultures (CM17 and CM6) and 3 different long-term control CB cultures (CB952A, CB935A, and CB56).

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