Effect of mAb to α4, αE, β1, or β7 integrins on MCp recruitment to the inflamed lung of BALB/c mice. (A) Number of lung MNCs per mouse recovered from OVA-sensitized BALB/c mice not challenged (No Chall) or from mice that had been given injections of HBSS (HBSS) or the indicated mAb and then challenged with aerosolized OVA. Values are the mean ± SEM from 4 separate experiments with following determinations in each group: HBSS (6); anti-αE (3); anti-α4 (3); anti-β1 (5); anti-β7 (8). (B) Concentration of MCp's (MCp's/10⁶ MNCs) in the lungs of the same mice. (C) Total number of MCp's per mouse in the lungs of the same mice. ^*Indicates statistical significance (P < .05) as determined by the 2-tailed Student t test.